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A clinical pilot study

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You may consider clinical assessment if: Pigmentation is long-standing or resistant to topical care Melasma remains persistent despite conservative management Post-inflammatory hyperpigmentation does not gradually fade Sun damage is extensive Treatment recommendations should always be individualised after medical evaluation

Recent studies indicated that TMZ plays a significant role in inducing ferroptosis in glioma cells, representing a novel mechanism to counteract the drug resistance commonly observed in glioma treatments

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